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Basic Guide to Using Misoprostol at Home Misoprostol is a safe and effective pill for terminating a pregnancy at home if you are within the first 12 weeks. You can use 4 pills sublingually (under the tongue), letting them dissolve for 30 minutes without swallowing, and repeat the dose every 3 hours until you complete 3 doses. It is normal to experience cramping, bleeding, and passing clots. Bring someone you trust with you and have sanitary pads, water, and a quiet space.
Do not use tampons or douches.
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